Comparative bactericidal effects of azlocillin and ticarcillin against Pseudomonas aeruginosa
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چکیده
منابع مشابه
Comparative bactericidal effects of azlocillin and ticarcillin against Pseudomonas aeruginosa.
Azlocillin was relatively ineffective against actively growing cultures of Pseudomonas aeruginosa in tests of bacteriolytic and bactericidal activity in which ticarcillin demonstrated pronounced bactericidal effects over a wide range of concentrations. Microscopic observation showed that azlocillin generally induced the formation of filamentous cells of P. aeruginosa which lysed only slowly, bu...
متن کاملBactericidal Effect against Pseudomonas Aeruginosa
Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan Department of Pathology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan Central Laboratory, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan Department of Microbiology, Kyoto University Graduate of Medicine, Kyoto, Japan Professor emeritus, Nagasaki Uni...
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The activities of N-formimidoyl thienamycin and azlocillin were compared with those of tobramycin, gentamicin, amikacin, and ticarcillin against 175 Pseudomonas aeruginosa isolates, including 24 strains with known mechanisms of resistance to aminoglycosides. The 50% mean inhibitory concentration for azlocillin was lower than for ticarcillin, but the 90% mean inhibitory concentration was similar...
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Azlocillin and tobramycin were used alone and in combination in the treatment of chronic osteomyelitis due to Pseudomonas aeruginosa in rabbits. This combination showed in vitro synergy measured by both the checkerboard technique and time-kill curves. A marked inoculum effect was demonstrated in vitro with azlocillin and the infecting strain of P. aeruginosa. The minimal inhibitory concentratio...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1980
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.18.1.182